They found there was a 40% reduction in the risk of death and a 35% reduction in the risk of the cancer returning within five years.<\/p>\n
When the initial results were announced in October 2023, Cancer Research UK said it showed the biggest improvement in cervical cancer treatment in more than 20 years.<\/p>\n
“This approach is a straightforward way to make a positive difference, using existing drugs that are cheap and already approved for use in patients,” said Dr Mary McCormack, lead investigator of the trial from UCL Cancer Institute and UCLH.<\/p>\n
<\/div>\n
“It has already been adopted by some cancer centres and there’s no reason that this shouldn’t be offered to all patients undergoing chemoradiation for this cancer.”<\/p>\n
Chemoradiation has been used to treat cervical cancer since 1999 but under the current process, cancer returns in up to 30% of cases.<\/p>\n
The Interlace phase III trial, funded by Cancer Research UK and UCL Cancer Trials Centre, studied whether a short course of induction chemotherapy prior to chemoradiation could cut death and relapses among patients with locally advanced cervical cancer that had not spread to other organs.<\/p>\n
“Timing is everything when you’re treating cancer,” said Dr Iain Foulkes, executive director of research and innovation at Cancer Research UK.<\/p>\n
“The simple act of adding induction chemotherapy to the start of chemoradiation treatment for cervical cancer has delivered remarkable results in the Interlace trial.”<\/p>\n
The researchers studied 500 patients over 10 years from hospitals in the UK, Mexico, India, Italy and Brazil.<\/p>\n
Patients were randomly allocated to receive either standard treatment or the new treatment combination.<\/p>\n
After five years, 80% of those who received a short course of chemotherapy first were alive and 72% had not seen their cancer return or spread.<\/p>\n
In the standard treatment group, 72% were alive and 64% had not seen their cancer return or spread.<\/p>\n<\/p>\n
This post appeared first on sky.com<\/div>\n
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A new cervical cancer treatment cuts the risk of death by 40% according to a large-scale study. Researchers at UCL and its associated hospital, University College London Hospital, spent 10 years studying patients who were given a short course of chemotherapy before chemoradiation, which is a combination of chemotherapy and radiotherapy. They found there was <\/p>\n","protected":false},"author":1,"featured_media":8697,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":{"0":"post-8696","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-science"},"_links":{"self":[{"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/posts\/8696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/comments?post=8696"}],"version-history":[{"count":0,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/posts\/8696\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/media\/8697"}],"wp:attachment":[{"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/media?parent=8696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/categories?post=8696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/digitaltradecenter.com\/index.php\/wp-json\/wp\/v2\/tags?post=8696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}